Epigenetics is the study of how behavior and the environment can cause changes in genes. Epigenetic modifications include reversible, inherited but non-genetic changes, while epigenomics refers to the analysis of all these epigenetic modifications. With our epigenomic analysis services, we help you unravel complex genomic processes. This will tell you how behavior and the environment can cause changes in genes.
Chromatin Immunoprecipitation Sequencing Chromatin immunoprecipitation followed by sequencing (ChIP-Seq) is a technique for genome-wide profiling of DNA binding proteins, histone modifications or nucleosomes. ChIP-Seq data is crucial to identify protein-DNA interactions, which can give clues on epigenetic modifications.
Methylation Sequencing DNA methylation is an epigenetic modification on DNA affecting only the Cytosine (C) base followed by Guanosine (G). Methylation Sequencing (Methyl-Seq) enables the identification of CpG sites. This is important since methylation is a source of genomic stability or gene silencing, leading to several diseases.